Osteoporosis is a skeletal systemic disease with a higher incidence in women than in men. This results in decreased bone mass and microarchitectural deterioration of bone. We could say that is a silent disease that is found when there is a broken bone.
The most common fractures are wrist, femur and vertebrae.
Aging is one of the causes of osteoporosis but also found genetic and hereditary factors. A poor diet, lack of exercise but especially menopause is one of the factors that most influence the occurrence of the disease in women.
Cannabinoids regulate many physiological functions and its impact on the immunity is generally anti-inflammatory as potent modulators of cytokine cascade. This powerful anti-inflammatory effect has contributed preclinical data in which an efficacy of cannabinoids in complex diseases such as osteoporosis is demonstrated.
Studies have concluded that endocannabinoids and their receptors are involved in the pathogenesis of osteoporosis. It has been found that pharmacological and genetic inactivation of CB1, CB2 and GPR55 receptors in adult mice increase bone mass suppress bone resorption and protect against bone loss. This means that the CB1 and CB2 receptor agonists and antagonists can prevent or even reverse the disease osteoporosis and other bone diseases.
A large number of medical researchers believe that the oil rich hemp CBD is a potent treatment for osteoporosis. The endocannabinoid system promotes healing fractures and the development of new bone tissue. Terpenes (cannabinoid) found in Cannabis promote general health.